Pdf a pair of male monozygotic twins, both affected by progeria is. Hutchinsongilford progeria syndrome hgps also known as childhood progeria is a rare. Hutchinsongilford progeria syndrome hgps is a rare condition originally described by hutchinson in 1886. Foi descrita, pela primeira vez, em 1886, por hutchinson, e ratificada por gilford, em 1904. Hutchinsongilford syndrome ileana olteanu, maria crisan, diana crisan, andrei kozan iuliu hatieganu university of medicine and pharmacy, clujnapoca, romania abstract. Eriksson m1, brown wt, gordon lb, glynn mw, singer j, scott l, erdos mr, robbins cm, moses ty, berglund p, dutra a, pak e, durkin s, csoka ab, boehnke m, glover tw, collins fs. Hutchinsongilford progeria, science, 3005628, 2055. Because of its rarity, lack of reporting and long term follow up prompted us to report this rare syndrome. Consent the examination of the patient was conducted.
Death result from cardiac complications in the majority of cases and usually occurs at average age of thirteen years. It is a rare genetic disease, which manifests by an accelerated senescence process of tissues and organs, without mental impairment. Hutchinson gilford progeria syndrome hgps is a sporadic, autosomal dominant disorder characterized by premature and accelerated aging symptoms leading to death at the mean age of 14. Progeria is an extremely rare autosomal dominant genetic disorder in which symptoms. It is characterized by premature aging that is 7 times higher than normal.